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Inhibition or disruption of their function can lead to faulty chromosome segregation (Ditchfield et al, 2003

Among these preliminary studies, one found that, in cultured cells, Protandim activated Nrf2, a protein that stimulates genes that respond to free radicals and oxidative stress, and another found it to improve markers of oxidative stress in mice (Reuland, Free Radic Biol Med 2013