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189 Further, ME1 treated with the inhibitor (piperazine-1-pyrrolidine-2,5-dione) has little effect on normal rat intestinal epithelial cells but strongly suppresses human CRC cell growth by targeting ME1 NADP + -binding site and reducing the NADPH level

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In any case, that a substance has been used as an adaptogen is not evidence of efficacy, but it is enough to obtain an NPN

As seen from Table 1, the deuterated analog (Example 2) of the invention displayed some stability over time with Ti 2 extended to 74.63 min