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We hypothesize that some sorts of conformational changes in the aptamer could occur upon binding to CspZ, leading to the observed biphasic association curves

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Validated stability indicating liquid chromatography method was used for separating the methylcobalamin and its degradation products

45,46 Increasingly, more studies have shown that G6PD activity is increased in several types of cancers, including bladder, breast, prostate, gastric cancers compared with normal tissues, and the high expression of G6PD predicts poor clinical outcome in various cancer patients and plays critical roles in tumorigenesis and chemoresistance