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Because skincare is not only about what we apply outside

USA 100 , 41444149 (2003)

Coy, J.-C

It plays a crucial role in detoxifying harmful substances, fighting free radicals, and supporting the immune system

LPS-induced miR-21-3p overexpression increased the protein and mRNA levels of the inflammatory cytokines monocyte chemoattractant protein-1 (MCP-1) and IL-6 in RPE cells while elevating apoptosis, caspase-3 activity, and levels of cleaved caspase-3 and poly-(ADP-ribose) polymerase proteins, which exacerbate inflammatory responses and apoptosis

elegans cannot de novo synthesize sterols as they lack genes for squalene synthase and cyclase (34), and they require dietary cholesterol for development (35)