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Dai, CBG-CS-2 strain, isolated from Cordyceps spp

[47] demonstrated that in mammalian cells, HIF-1 reciprocally controlled cytochrome c oxidase 4 (COX4) subunit expression under circumstances of low O 2 availability by promoting transcription of the genes encoding COX4-2 and LON, a mitochondrial protease necessary for COX1-1 breakdown

Wilcken NR, Prall OW, Musgrove EA, Sutherland RL

The homogenate was centrifuged at 10,000 g for 20 min at 4 C, and the resulting supernatant was collected for subsequent analysis

However, it only increases the percentage of the EFSAs acute reference dose (ARfD) of 20 g/kg body weight from 7.4% to 8.9% (lower bound) or from 13% to 15% (upper bound), which is negligible for people with normal kidney function

Among them, we can highlight DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport and enzyme activation