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Lipid metabolic disorders can cause nutritional iron deficiency in the body, disrupt iron homeostasis, and induce lipid peroxidation, accumulating LPO to directly damage cell membranes, leading to cellular dysfunction and ferroptosis (Ali-Rahmani et al., 2014

Maintenance of remission in inflammatory bowel disease using omega-3 fatty acids (fish oil): a systematic review and meta-analyses

doi:10.1080/19490976.2017.1284732 182

Furthermore, the heme-export efficiency of FLVCR1a is directly proportional to the affinity of the extracellular protein for heme (Yang et al., 2010)

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Amino acids are transported by systems which are broadly defined based on their physiochemical properties and substrate specificity [66]