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3T3-L1 cell viability was only slightly reduced at the highest tested concentration of 5-amino-1MQ compared to untreated cell viability (P 0.05

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The peptide known as AOD-9604 may help stimulate appetite reduction, accelerate fat metabolism, and support bone health without these adverse side effects

5-Amino-1MQ inhibits NNMT activity, preserving nicotinamide for NAD+ synthesis and preserving SAM for epigenetic methylation producing a metabolic state in pre-clinical models that has been described as functionally resembling caloric restriction or elevated physical activity at the cellular level

J Biol Chem (1951) 189(1):20316