mk571 mrp1 glutathione efflux inhibitor MK-571 shifts cellular thiol pools, further potentiating MRP1 modulators synergize with buthionine

MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1 expressing cancer cells ScienceDirect Mechanisms of glutathione disulfide efflux from erythrocytes ScienceDirect Glutathione transporters. Plasma membrane GSH efflux pumps . Two GSH Download Scientific Diagram The gut efflux pump MRP 1 exports oxidized glutathione as a danger signal that stimulates behavioral immunity and aversive learning Communications Biology In vitro function and in situ localization of Multidrug Resistance associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury induced oxidative stress in the human placenta Archives of Toxicology Springer In differentiated HL 60 neutrophil like cells, MRP1 (ABCC1 ) mediated glutathione efflux stimulated by BzATP and P2X7 receptor signalling regulates exosome release through nSMase activity bioRxiv

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