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One drink early in the day is far less damaging than 2 to 3 drinks close to bedtime: timing matters more than total volume

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While HRT can improve energy, libido, and bone health , it carries risks such as cancer, cardiovascular disease, and blood clots Rossouw et al., JAMA , 2002

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The remaining 5% to 10% are produced by the anaerobic glycolysis pathway, degrading glucose to pyruvate