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In experimental systems, DSIP has been explored for its potential ability to influence the stability and duration of these delta-dominant sleep cycles

At the metabolomics level, the fatty acid biomarkers identified include capric acid, caproic acid, propionic acid, and heptanoic acid and showed a significant reduction in at least one of the severity groups listed above, compared to the healthy controls and the concentration of the uremic toxins IS and p-CS were significantly high at the advanced stage

The intensity of Sirius red staining was significantly higher in treated animals than in control groups at all three-time intervals (Figure 11)

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doi: 10.1080/07352689.2020.1866829 8 ArahI

Postural stability and reaction time measures assessing physical control and responsiveness