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For example, inflammatory mediators increase BBB permeability, allowing the delivery of larger molecules

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Behavior was recorded for 10 min using an automated tracking system to quantify: ( 2.4 Y-maze Spatial working memory was evaluated using a symmetrical acrylic Y-maze (This experiment was performed on day 7 after CLP surgery) consisting of three arms (35 cm in length, 5 cm in width, 15 cm in height) positioned at 120 angles to each other

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