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However, for improved evaluation of methylation balance, SAMe: SAH ratio is recommended as it defines methylation potential of the cell

on the other hand, it complicates pinpointing mechanisms and predicting off-target effects

Lew VL, Raftos JE, Sorette M, et al

The expression of HIOMT was significantly increased in ulcerative colitis and lymphocytic colitis patients compared with that in healthy subjects (Wu, 2021b)