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Human TrxR is a selenoprotein (27)

FEMS Microbiol Lett 219:187194 Lagrain B, Thewissen BG, Brijs K, Delcour JA (2007) Impact of redox agents on the extractability of gluten proteins during bread making

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If a deficiency is detected, your doctor may recommend vitamin B12 injections, which are often more effective than oral supplements due to metformins impact on stomach absorption