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These changes have been associated with increased intestinal permeability, elevated systemic endotoxin levels, and immune dysregulation, all of which may contribute to the development and progression of thyroid dysfunction (Miquel et al., 2013

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DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis

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doi: 10.2337/db11-0465 [DOI] [PMC free article] [PubMed] [Google Scholar] 52.Eftekhari MH, Akbarzadeh M, Dabbaghmanesh MH, et al