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S6K can also phosphorylate programmed cell death 4 (PDCD4), putting it at risk of degradation by the ubiquitin ligase Beta-TrCP

Merck KGaA, Darmstadt, Germany) was premixed with enzymes (10 nM for each) for 30 min prior to the addition of 200 M adenosine triphosphate (ATP), 1.2 mM glutamic acid and 200 M cysteine

PMID 18044098

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In fact, the opposite is usually true

Sphingolipids: regulators of crosstalk between apoptosis and autophagy