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Upregulation of SKP2 can facilitate the expression of mRNA for serine/threonine kinases and transferrin receptors, thereby contributing to ferroptosis (263)

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Regular follow-up blood tests help confirm the therapy is working

Figure 1 illustrates changes within key pathways evaluated after 8 weeks of treatment

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and (6) Priming and Repriming establishing the actuations needed before consistent dosing is achieved