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Secondary degeneration reduced by inosine after spinal cord injury in rats

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This translocation leads to the release of AIFM1 from mitochondria, which subsequently forms a complex with macrophage migration inhibitory factor (MIF) in the cytoplasm [154]

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22,23 At the same time, oxygen free radicals can also indirectly trigger the deterioration of the inflammatory response in ARDS patients by inducing the stimulation of inflammatory cells and promoting the inflammatory cytokines production