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found that in aortic valve stenosis, exogenous H 2 S activates the NRF2SQOR pathway, upregulating SQOR and NRF2 and inducing autophagy as well as antioxidant genes (e.g., NQO1 , CSE )

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Research has shown that alcohol stimulates hepatocytes to release extracellular vesicles containing CD40L in a caspase-3-dependent manner [167], thereby activating macrophages and increasing the production of inflammatory cytokines

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Tosic M, Ott J, Barral S, Bovet P, Deppen P, Gheorghita F, et al

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Abstract The decreases in the glutathione (GSH) level in the mouse spleen and liver after immune stimulation are suppressed by the oral administration of cystine and theanine (CT)

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