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Moreover, fennel's anti-inflammatory effects are underscored by its ability to modulate key pathways involved in inflammation and oxidative stress, contributing to improved insulin sensitivity and metabolic profiles in diabetic models

Carotenoids of biotechnological importance

FFAs also indirectly cause mitochondrial injury by inducing lysosomal permeabilization, which causes activation of pro-apoptotic members of the Bcl-2 family that subsequently induce mitochondrial permeabilization and apoptotic cell death [70, 71]

However, the scope of both changes, although statistically significant, was within the limits of accepted norms for healthy people

Ye P, Li W, Huang X, Zhao S, Chen W, Xia Y, Yu W, Rao T, Ning J, Zhou X, Ruan Y, Cheng F (2022) BMAL1 regulates mitochondrial homeostasis in renal ischaemia-reperfusion injury by mediating the SIRT1/PGC-1 axis

We used an ethylnitrosourea (ENU)-induced malignant GBM pregnant rat model developed from Koestner et al