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Genetic variants in FTO and MC4R can indirectly affect energy regulation during sleep-wake cycles

Santacruz et al., 2010)

24 Besides, NADPH acts as the reducing reagent for 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), the rate-limiting enzyme of the mevalonate pathway, which leads to the synthesis of cholesterol and nonsterol isoprenoids

Fallon MT, Storey DJ, Krishan A, Weir CJ, Mitchell R, Fleetwood-Walker SM,

Blood-based bioenergetic profiling reveals differences in mitochondrial function associated with cognitive performance and Alzheimers disease

doi: 10.1016/j.cophys.2020.06.012 85 IvanovAIParkosCANusratA