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A common protocol for patients with a B12 deficiency may be 1,000 mcg daily for one week, then the same dosage once weekly, and then the same dosage once per month after the deficiency has been addressed

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Practical Summary Protocol Step 1 (True Baseline): Establish a true baseline by drawing fasting plasma TMAO before initiating any ET supplementation

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However, in the case of CD, its important to note that while adaptive immunity can perpetuate inflammation, it doesnt trigger the initial inflammation (65)