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For instance, miR-21 promotes CD4 + T cell glycolysis through the PTEN/PI3K/AKT pathway, which increases the cell cycle, promotes CD4 + T cell polarization toward the Th2 phenotype, and releases the fibrogenic cytokine IL-13, which is involved in arsenite-induced hepatic fibrosis [110] (Fig

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The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm

VEGF-A from granuloma macrophages regulates granulomatous inflammation by a non-angiogenic pathway during mycobacterial infection

In addition, increased methylation of the DTNBP1 gene, observed in both schizophrenia patients and their first-degree relatives, was partially reversed with antipsychotic treatment (Abdolmaleky et al., 2015)

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