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The significance of this paper is not only to compare the three routes of administration but also to evaluate them and determine which route is the best to administrate the drug

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The strongest support comes from clinical evidence focused on treating vitamin B12 deficiency, not from general wellness claims What science supports The NIH Fact Sheet for Health Professionals shows that intramuscular B12 injections are effective at raising blood B12 levels and correcting deficiency

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Symptoms of a Vitamin B12 deficiency in chickens include: Vitamin B12 Deficiency in Growing Chicks increased mortality reduced weight gain and feed intake poor feathering enlarged thyroid glands gizzard lesions nervous disorders Vitamin B12 deficiency in laying hens Production of smaller-sized eggs decrease in egg weight Vitamin B12 deficiency in breeders Decrease hatchability Vitamin B12 deficiency in developing embryos from Vit