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Description

10.3233/JAD-170543 12 AmorosoR.MaccalliniC.BellezzaI

Methylated DNA is recognized by a protein called the methyl-CpG-binding domain (MBD), which recruits other proteins to sites, such as histone deacetylases and other chromatin remodeling factors that can modify histones, to form dense, inactive heterochromatin, thereby inhibiting gene transcription