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If you have anemia, which is not caused due to iron-deficiency

This was not based on a formal power calculation but was within the standard range of participants in pharmacokinetic studies of people with renal impairment [13]

28-day, ICU and in-hospital mortality The odds of 28-day mortality and in-hospital mortality was reduced in PCT guidance compared to SOC, the former being statistically significant (OR 0.84, 95% CI: 0.74, 0.95, p = 0.008 (Additional file 1: Figure S2) and OR 0.85, 95% CI: 0.66, 1.10 (Additional file 1: Figure S3), respectively)

MOTSc is studied in preclinical models to better understand metabolic signaling (how cells coordinate energy use), cellular energy regulation (how cells respond when energy demand changes), and mitochondrial homeostasis (how mitochondria maintain stable function)

Abbreviations AE: Adverse event AUC 0t : Area under the plasma concentration-time curve from time zero to time AUC 0 : Area under the curve from time 0 extrapolated to infinity AUC _%Extrap : Greater than 20% extrapolation BMI: Body mass index CI: Confidence interval C max : Peak plasma concentration ECG: Electrocardiogram HPLC-MS/MS: High-performance liquid chromatographytandem mass spectrometry PK: Pharmacokinetic SAE: Serious adverse event T max : Time to reach the peak plasma concentration t 1/2 : Elimination half-life z : Elimination rate constant References Gao Q, Zhen K, Xia L, et al