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Indeed, the pediatric autoimmune neuropsychiatric disorder associated with group A -hemolytic streptococcus (GABHS) (PANDAS) and thus the recalled pediatric acute neuropsychiatric syndrome (PANS) have highlighted that several agents rather than streptococcus could be involved in these acute-onset forms of OCD 48

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In addition, once-daily administration of 1 mg oral hydroxocobalamine caused the studied children's levels of homocysteine to increase and their levels of methionine to decrease, while the reverse happened when hydroxocobalamine was given intramuscularly

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The primary ions used to calculate the pH of water are Hydrogen (H+) and Hydroxyl (OH-)