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In the same study, elevated expression of inflammatory genes was also linked with decreased thickness of the subgenual ACC, hippocampus, and caudate in the mood-disordered group (213)

However, there are several issues in the field of neuroprotection in schizophrenia

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Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging