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Repetitive behavior and increased activity in mice with Purkinje cell loss: a model for understanding the role of cerebellar pathology in autism

Abdelmalek 3 , Philippe Huot-Marchand 1 , Lucile Dzen 1 , Martine Baudin 1 , Jean Louis Junien 1 , Pierre Broqua 1 and Michael Cooreman 4 , (1)Inventiva, (2)University of Antwerp, Edegem, Belgium, (3)Mayo Clinic, Rochester, MN, (4)INVENTIVA Background: A polymorphism of patatin-like phospholipase domain-containing protein 3 (PNPLA3), I148M, is strongly associated with the risk for and the progression of nonalcoholic steatohepatitis (NASH)

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