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as insulin secretion, the glycolytic and/or lipolytic potential of tissues, gluconeogenesis and likely most aspects of glucose and energy homeostasis have been found defective and implicated in the pathogenesis and/or progression of hypertension and MetS (Katsimardou et al., 2020)

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This bimodal behavior suggests that the binding of the respective ligand makes the protein take two distinct conformations throughout the MD simulation

Control groups received scopolamine or aCSF 20 min prior to testing followed by aCSF 10 min prior testing

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