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(Liu et al., 2022) conducted a longitudinal study involving Chinese community residents aged 65 years, revealing that HHcy escalates the risk of MetS, particularly among individuals with abdominal obesity

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In support of this idea, when holoTC concentrations were subtracted from total vitamin B-12 concentrations, the remaining vitamin B-12, represented by the holohaptocorrin (holoHC) fraction of serum vitamin B-12, was unaffected by the concentration of plasma folate (Figure 8B)