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Conclusion# NAD+ holds clear advantages over Epitalon in nearly every practical comparison: broader evidence base, human clinical data, multi-hallmark coverage, ease of administration, and commercial accessibility

doi: 10.1155/2021/9947370 82 MartineauARCatesCJUrashimaMJensenMGriffithsAPNurmatovUet al

Front Neurol 12:661955

The term 'synergy' gets used when two compounds produce slightly better results together than alonebut true synergy means the combined effect exceeds the sum of individual effects, and that requires targeting rate-limiting steps in a shared pathway

It is also important to consult with a healthcare provider before starting B12 shots, especially for those on medications that may interfere with B12 absorption or metabolism