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116,123-125 One randomized placebo-controlled trial that included 44 subjects, aged 50 to 70 years, with memory and concentration complaints, anxiety, and sleep problems found 12 weeks of magnesium L-threonate supplementation, at a dose of 1.52 grams per day depending on body weight, significantly improved overall cognitive performance relative to both baseline and placebo

doi: 10.1111/jgs.16430 Emergency Medicine (29): Rodney Borger, Eric Sechrist, Fanglong Dong, Carol Lee, Kaitlin Chon, Arianna Neeki , Lori Winston, Michael M Neeki

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The prodrug was stable in normal tissues but can be easily hydrolyzed into DON in P493B lymphoma cells, inhibiting tumor cell proliferation in a dose-dependent manner (Tenora et al., 2019)

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