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IF RT-PCR IF WB In Vivo Efficacy Study All Endogenous Metabolite Isoforms More Biological Activity [1] [2]

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The plasma clearance of parent BCNU decreases and the plasma half-life increases as doses escalate from standard-dose (150 to 200 mg/m2) to high-dose regimens (600 mg/m 2 ) (Table 14A-1)

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