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The link of SLC7A11 to GPX4 is further determined [34], SLC7A11 mediates cystine uptake, subsequently, activates Rag-mTORC14EBP pathway-induced GPX4 protein synthesis

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Phase 3 pivotal trials of 3-year treatment with this implant have met their primary endpoint with a favorable safety profile, but results have not been published

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849 In animal models of intestinal I/R, ferroptosis occurs primarily during the reperfusion phase due to the inactivation of the GSH/GPX4 pathway

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