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The 2024 NICE guideline asks clinicians to tailor timing to your symptoms and review it, rather than treating one figure as fixed

Vitamin B12 deficiency symptoms include numbness or tingling in the hands, legs, or feet, difficulty walking, anaemia, swollen tongue, weakness, fatigue, and cognitive difficulties, including memory loss

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Study selection This review aimed to synthesize evidence from clinical trials examining the role of opioid peptides in ASD and the potential impact of GFCF dietary interventions on opioid peptide concentrations in individuals with ASD