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Design, synthesis, and evaluation of a low-molecular-weight (11)C-labeled tetrazine for pretargeted PET imaging applying bioorthogonal in vivo click chemistry

10.1159/000331717 56 ZhangL.HuangB.ScherlagB

It is important to follow recommended dosing guidelines and consult a healthcare practitioner if you are pregnant, nursing, or taking medications

It is water-suspended, and the suspension was prepared by suspending it in sterile distilled water to make a stock every week 28

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Nonetheless, studies conducted in living organisms indicate that their concentrations are often insufficient to effectively traverse the bloodbrain barrier, limiting their bioavailability, stability, and dissolution at the intended brain sites