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Similar content being viewed by others Introduction The term redox is derived from the concepts of reduction and oxidation, which are processes that are pivotal for maintaining cellular homeostasis, regulating a wide array of cellular processes, and impacting the overall functionality of cells

In Stevens-Johnson syndrome and toxic epidermal necrolysis, keratinocytes exhibit imbalanced FSP1-CoQ10 antioxidant systems and increased lipid peroxidation, leading to ferroptosis and life-threatening skin adverse drug reactions characterized by keratinocyte death [93]