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Modest vasomotor dysfunction induced by low doses of C60 fullerenes in apolipoprotein E knockout mice with different degree of atherosclerosis

While this might suggest limited importance of the oxPPP in T reg cells, knockout of Pgd specifically in T reg cells (driven by Foxp3- Cre) causes severe T reg dysfunction in mice, which die because of autoimmunity between days 20 and 30 of life 119

Increases mobility in peripheral artery disease Occlusive peripheral arterial disease is caused by atherosclerosis, which is a buildup of fatty deposits in the artery

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Similarly, in vitro binding assay with recombinant GSTO1 was performed using 1 M GSTO1 in reaction buffer (100 mM Tris (pH 8.0), 1.5 mM EDTA and 1 M DTT) incubated with compounds for 30 min at 37 C and with CMFDA (500 nM) for an additional 30 min

Wentzel AS, Janssen JJE, de Boer VCJ, van Veen WG, Forlenza M, Wiegertjes GF