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doi: 10.1038/s41467-018-04639-1 [DOI] [PMC free article] [PubMed] [Google Scholar] 184

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Gomes et al 3 showed that, compared to nonmetastatic breast cancer cells, metastatic breast cancer cells downregulate an enzyme of the propionate metabolism pathway, methylmalonyl-CoA epimerase, which leads to an intracellular accumulation of MMA and fuels metastasis