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SKU: 97256346715
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Specifically, dysregulated neuronal energy metabolism can trigger apoptotic cascades via mitochondrial membrane potential collapse or abnormal pyruvate dehydrogenase complex phosphorylation, while targeting monocarboxylate transporter MCT2-mediated lactate shuttling or mitochondrial calcium uniporter (MCU) activity has emerged as a promising therapeutic strategy for neurodegenerative disorders

In contrast, it significantly improves anti-PD-1 responses in PD-1 refractory microsatellite stable CRC

Senescent macrophages release inflammatory cytokines and RNA-loaded extracellular vesicles to circumvent fibroblast senescence

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