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doi: 10.1038/cdd.2010.6 155 BirkenmeierGHemdanNYAKurzSBiglMPierohPDebebeTet al

This pathway, catalyzed by betaine-homocysteine methyltransferase, mainly occurs in the liver

Parkes RJ, Hart SL

For example, variations in NOD2 are associated with the fibrotic-stricturing phenotype of CD [175], whereas variations in the human leukocyte antigen (HLA) region affect the disease extent and severity of UC [199]