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J Pharmacol Exp Ther 302:5057 Perez-Mato M, Ramos-Cabrer P, Sobrino T, Blanco M, Ruban A, Mirelman D, Menendez P, Castillo J, Campos F (2014) Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia

Notably, SHMT2 is a mitochondrial enzyme contributory to one-carbon metabolism by converting serine and tetrahydrofolate (THF) into glycine for GSH synthesis and a one-carbon unit, 5,10-methylenetetrahydrofolate (5,10-CH 2 -THF), for dTTP synthesis 35 , respectively

It plays a role in normal collagen production, which helps support the structure of skin

Centre du Champ de Mars Palais royal Adresse Notre Centre A quelques minutes du muse du Louvre, situ en plein centre de Paris, le Centre du Champ de Mars Palais Royal stend sur plus de 450m2 ddis notamment la mdecine esthtique

pAAV-TBG-GFP, with the same backbone but expressing GFP, was used as a control

7 Conclusion This review summarizes the latest advances in drug resistance mechanisms and the clinical translation of High-Grade Serous Ovarian Carcinoma (HGSOC)