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The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes PubMed

In contrast, the endogenous ubiquitin-proteasome system (UPS) represents a natural regulatory mechanism that maintains proteostatic balance by selectively tagging and degrading damaged or unwanted proteins [17,18,19,20]

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Further investigation revealed minimal impact of Tripterygium wilfordii on NLRP3/caspase-1 levels in MPTP-treated Nrf2-KO mice, suggesting that the extract may exert its anti-PD effects by activating Nrf2 to subsequently inhibit the NLRP3 inflammasome (Figure 4)