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Nevertheless, certain conditions can impact the absorption or intake, hence often leading to deficiency, for example, pernicious anemia or if the individual follows a vegan diet

Furthermore, gut microbiota dysbiosis and altered gut microbial metabolite synthesis, such as short-chain fatty acids (SCFAs), can impact neuronal signaling and cognitive processes

Hence the mutation is likely to have a deleterious effect

In vitro metabolism studies identify how peptides break down

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It is well established that administration of KA results in astrocyte and microglia activation, which is known as gliosis