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Some patients benefit from weekly injections during periods of low energy, weight loss, or high stress, while others prefer biweekly or maintenance dosing once they feel more stable

Direct the water against the inner wall of the vial as it is injected never onto the lyophilized cake, since direct impact foams the solution and denatures compound at the air-water interface

This means that unexplained, persistent high B12, especially when it is not caused by supplements, should not be ignored

This can reduce or eliminate pain

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