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However, an unrestricted KD alone failed to control tumor growth, underscoring the need for combination approaches such as glycolysis inhibitors or antiangiogenic agents targeting non-oxidative pathways [146]

255 UPS regulation of cell cycle progression and metabolic reprogramming The UPS tightly controls cell cycle regulators, such as cyclins and cyclin-dependent kinase (CDK) inhibitors, whose dysregulation is common in cancer

Biol Pharm Bull (2018) 41:55563

officinalis leaves and studied its impact on the proliferation and migration of human malignant melanoma cells (A375) and STAT3 signaling

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The reduction of fibroid size and uterine volume may allow for an easier or less invasive surgery, and in some cases to avoid it [49]