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In summary, GLPs regulate systemic glucose homeostasis via a multi-tiered, integrative mechanism: they inhibit excessive hepatic glucose production by downregulating key gluconeogenic enzymes and suppressing glycogenolysis

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[Google Scholar] [PubMed] [CrossRef] Sairenji T, Collins KL, Evans DV (2017)

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Gap junctional transmission was substantially greater in hepsin / mice, likely due to the elevated expression of Cx32