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Symptoms may include: Constantly feeling tired or chronic fatigue Muscle aches and weakness Joint pain Difficulty breathing or shortness of breath Feeling dizzy Poor memory Inability to concentrate well Mood changes, like increased depression and anxiety Having abnormal heart problems, such as palpitations Poor dental health, including bleeding gums and mouth sores Digestive problems like nausea, diarrhea or cramping A poor appetite A more serious deficiency can also cause a form of anemia called pernicious anemia, a serious condition that can cause memory loss, confusion and even long-term dementia

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This is the second head-to-head study after Eli Lilly registered its intent to carry out a Phase 3b clinical trial in April 2023 that will see the companys tirzepatide (Mounjaro) compared with Novo Nordisks semaglutide (Wegovy) 2.4mg in 700 adult participants who have obesity or overweight with weight related comorbidities without Type 2 diabetes

Semaglutide belongs to the class of GLP-1 receptor agonists, administered via a once-weekly injection

KozyrakiRFyfeJKristiansenMGerdesCJacobsenCCuiSet alThe intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein