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Neelakantan et al., 2018

In some tumor types, NNMT activity helps the tumor grow

Depletion of the microbiome alters the recruitment of neuronal ensembles of oxycodone intoxication and withdrawal (in Eng)

5-Amino-1MQ was selected for further work because of its potency, permeability and selectivity in the tested systems

Rather than manipulating hormones, suppressing appetite, or artificially stimulating the nervous system, it works at the level of basic cellular energy production and storage