BMC Res Notes2010;3:22
That said, a PCAC vote is advisory, not binding, meaning real-world access for patients hasn't changed
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A more gradual rise in blood levels could reduce the sharp peak that triggers GI side effects in sensitive individuals
Recent studies looking at the telomeric proteome during replication observed high levels of histone protein H1 at telomeres during replication (Lin et al 2021), and cells that had H1 depleted through knockout experiments are sensitive to DNA damage and double strand breaks (Murga et al 2007)
